Director of Public Health Annual Report 2022: Preventing heart disease and stroke in Buckinghamshire

3.4 People with severe mental illness

People with a severe mental illness (schizophrenia, bipolar disorder, and major depressive disorder) have more than a 50% higher risk of having cardiovascular disease and an 85% higher chance of dying from cardiovascular disease compared with people of similar age.[141]

People with SMI are more likely to develop cardiovascular disease at an earlier age.[142] Certain risk factors for cardiovascular disease are more common in people with SMI, such as smoking and alcohol consumption.[143] In addition, obesity and diabetes are more common and some (but not all) of this association may be explained by metabolic effects of some medication.[144]